Health Care

Probiotic, Oral Therapy Work, Study Shows — Peanut Allergy Cure

Probiotic, Oral Therapy Work, Study Shows — Peanut Allergy Cure”

"These children had been eating peanut freely in their diet without having to follow any particular program of peanut intake in the years after treatment was completed", said lead researcher Professor Mimi Tang.

"Ours is the first study to show prolonged eight-week sustained unresponsiveness several years after treatment has ceased and suggests the possibility that tolerance is a realistic target for food allergy treatments".

The Murdoch Childrens Research Institute joined with a capital investment firm called OneVentures past year to develop the treatment into an FDA-approved product.

A small clinical trial conducted at Murdoch Children's Research Institute helped two-thirds of children rid of their allergy to peanuts through experimental immunotherapy.

"The importance of this finding is that these children were able to eat peanut like children who don't have peanut allergy and still maintain their tolerant state, protected against reactions to peanut".

The Independent said roughly one per cent of the world's population suffers from peanut allergy, which is also one of the planet's most severe food allergies, commonly associated with anaphylaxis, a life-threatening reaction.

The researchers said the study provides the "strongest evidence yet that a cure may be possible for peanut allergy".

A total of 48 children were enrolled in the PPOIT trial and were randomly given either a combination of the probiotic, Lactobacillus rhamnosus, together with peanut protein in increasing amounts, or a placebo, once daily for 18 months.

"The probiotic acts on the immune system, encourages the immune system to generate a protective, or tolerance, response rather than allergy", she said.

According to Mimi Tang, "this is a major step forward in the identification of a treatment for food allergies in western societies".

In the worst-case scenario, peanut allergies can cause anaphylaxis, which can kill.

Food allergies affect one in 20 children and two adults out of 100, with the most prevalent being the reactions to seafood, cow's milk, eggs, and peanuts.

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