Health Care

Type 2 diabetes remission a 'practical target for primary care'

Type 2 diabetes remission a 'practical target for primary care'”

The Diabetes Remission Clinical Trial (DiRECT), funded by Diabetes UK and published today in the Lancet, found that after 12 months nearly half of participants had achieved remission to a non-diabetic state on an intensive calorie controlled programme that did not involve prescribing or increasing antidiabetes medication.

Almost half - 68 participants - had reversed their diabetes within one year of starting the trial, compared to six in the control group. Almost half the people who underwent the diet saw their condition go into remission - providing the strongest evidence yet that diabetes can be eradicated by simply losing weight.

Among those who lost 33Ibs or more, 86 per cent reversed their diabetes. Participants could not be taking insulin replacement and were taken off anti-diabetes drugs and anti-hypertensive medication.

Type 2 diabetes is usually treated with medication and in some cases, bariatric surgery to restrict stomach capacity, which has also been shown to reverse the disease.

He added that Global Positioning System should encourage patients to lose weight as soon as possible after the condition is diagnosed.

Professor Lean added: "Putting type 2 diabetes into remission as early as possible after diagnosis could have extraordinary benefits, both for the individual and the NHS".

"DiRECT is telling us it could be possible for as many as half of patients to achieve this in routine primary care, and without drugs".

Worldwide, the number of people with type 2 diabetes has quadrupled over 35 years, rising from 108 million in 1980 to 422 million in 2014. It can lead to serious and life-threatening complications, including blindness and foot amputations, heart and kidney disease. In Scotland alone, diabetes drugs are costing the NHS £90 million a year - up from £73.2m in 2012/13.

Prof Roy Taylor from Newcastle University, lead researcher in the trial funded by Diabetes UK, said: "These findings are very exciting".

Separately, another multi-centre randomly controlled trial called PREVIEW - Prevention of diabetes through lifestyle intervention of population studies in Europe and around the world - is looking at the use of very low energy diets to prevent people from becoming diabetic in the first place. "Bariatric surgery can achieve remission of diabetes in about three-quarters of people, but it is more expensive and risky, and is only available to a small number of patients".

A new study discovered that weight loss really can cure diabetes. "The big challenge is long-term avoidance of weight re-gain", he said.

A follow-up study over the next four years will determine whether weight loss and remission are achievable long-term. Professor Taylor said: 'Substantial weight loss results in reduced fat inside the liver and pancreas, allowing the organs to return to normal function'. But a year after starting the 850-calorie-a-day diet, 75 percent were drug free and 46 percent had seen their blood sugar drop so far they were no longer considered diabetic.

Dr Andrew Green, the BMA GP Committee's prescribing lead, welcomed the results.

'In the meantime, we need to stress to people with Type 2 diabetes the importance of speaking to their GP, and seeking their support, before trying any kind of low calorie diet'.

Like this


06 Декабря 2017
Facebook launches messaging app for under 13s
There has been criticism that the app was created to draw children in and groom them to eventually become regular Facebook users. Finish the setup process by creating an account for your child, where all you'll need to do is provide their name.

06 Декабря 2017
Lululemon athletica (LULU) PT Raised to $75.00 at Bank of America
Peoples Finance Svcs Corporation has invested 0.01% of its portfolio in Lululemon Athletica Inc . (NASDAQ:CSCO). Twin Tree Management Lp invested in 0% or 2,946 shares. 1,110 were accumulated by North Star Invest Mngmt Corp.

06 Декабря 2017
Apple Incorporated (NASDAQ:AAPL)'s Trend Up, Especially After Decreased Shorts
The iPhone maker reported $2.07 earnings per share for the quarter, beating the Zacks' consensus estimate of $1.87 by $0.20. With 27.44M shares average volume, it will take short sellers 1 days to cover their AAPL's short positions.

06 Декабря 2017
For Republicans, Gun Control And Gun Rights Can Be Linked
The review comes after the Las Vegas gunman used the so-called "bump stock" devices during the deadly October rampage. The Air Force has discovered several dozen other such reporting omissions since the November 5 shooting.

06 Декабря 2017
Luncheon celebrates our WWII veterans on Pearl Harbor anniversary
Clyde Rains; Vietnam Veterans of America Chapter 528, with President Richard Adis; and American Legion Post 391, with Cmdr. The Pearl Harbor naval base in Hawaii was the hub of United States naval power in the 1940s.

06 Декабря 2017
Sells 1516 Shares of Automatic Data Processing (ADP)
Automatic Data Processing, Inc . (NASDAQ: ADP ). 79,520 are held by Azimuth Cap Management Limited Liability Company. The volume of ADP witnessed a shift from 2.29 million shares, based on a 50-day average, to 2.41 million shares.

06 Декабря 2017
Here's How the Weather Will Change Pokemon Go
For example: the odds of discovering Mudkip will increase on rainy days; and Charizard's Fire Spin will perform better on sunny days.

06 Декабря 2017
U.S. airline makes emergency pit-stop for bathroom break
That meant there was no way for everyone to "find relief of built up pressures", the report said. After landing, the plane had to taxi to a cargo area because a gate was not available.

06 Декабря 2017
EasyJet will break Lufthansa's monopoly in its home skies
Its expansion into the larger inner-city Tegel airport will see EasyJet compete with Lufthansa on domestic flights out of Berlin . That drove the load factor - a common measure of capacity utilisation - up by 2.6 percentage points to 92.3 per cent.

06 Декабря 2017
Dallas Sheriff Lupe Valdez, former San Antonian, announces run for governor
Mark White, former San Antonio congressional candidate Tom Wakely, and Dallas businessman Jeffrey Payne. Abbott, now seeking a second term, often polls as the state's most popular elected official.