Health Care

Type 2 diabetes remission a 'practical target for primary care'

Type 2 diabetes remission a 'practical target for primary care'”

The Diabetes Remission Clinical Trial (DiRECT), funded by Diabetes UK and published today in the Lancet, found that after 12 months nearly half of participants had achieved remission to a non-diabetic state on an intensive calorie controlled programme that did not involve prescribing or increasing antidiabetes medication.

Almost half - 68 participants - had reversed their diabetes within one year of starting the trial, compared to six in the control group. Almost half the people who underwent the diet saw their condition go into remission - providing the strongest evidence yet that diabetes can be eradicated by simply losing weight.

Among those who lost 33Ibs or more, 86 per cent reversed their diabetes. Participants could not be taking insulin replacement and were taken off anti-diabetes drugs and anti-hypertensive medication.

Type 2 diabetes is usually treated with medication and in some cases, bariatric surgery to restrict stomach capacity, which has also been shown to reverse the disease.

He added that Global Positioning System should encourage patients to lose weight as soon as possible after the condition is diagnosed.

Professor Lean added: "Putting type 2 diabetes into remission as early as possible after diagnosis could have extraordinary benefits, both for the individual and the NHS".

"DiRECT is telling us it could be possible for as many as half of patients to achieve this in routine primary care, and without drugs".

Worldwide, the number of people with type 2 diabetes has quadrupled over 35 years, rising from 108 million in 1980 to 422 million in 2014. It can lead to serious and life-threatening complications, including blindness and foot amputations, heart and kidney disease. In Scotland alone, diabetes drugs are costing the NHS £90 million a year - up from £73.2m in 2012/13.

Prof Roy Taylor from Newcastle University, lead researcher in the trial funded by Diabetes UK, said: "These findings are very exciting".

Separately, another multi-centre randomly controlled trial called PREVIEW - Prevention of diabetes through lifestyle intervention of population studies in Europe and around the world - is looking at the use of very low energy diets to prevent people from becoming diabetic in the first place. "Bariatric surgery can achieve remission of diabetes in about three-quarters of people, but it is more expensive and risky, and is only available to a small number of patients".

A new study discovered that weight loss really can cure diabetes. "The big challenge is long-term avoidance of weight re-gain", he said.

A follow-up study over the next four years will determine whether weight loss and remission are achievable long-term. Professor Taylor said: 'Substantial weight loss results in reduced fat inside the liver and pancreas, allowing the organs to return to normal function'. But a year after starting the 850-calorie-a-day diet, 75 percent were drug free and 46 percent had seen their blood sugar drop so far they were no longer considered diabetic.

Dr Andrew Green, the BMA GP Committee's prescribing lead, welcomed the results.

'In the meantime, we need to stress to people with Type 2 diabetes the importance of speaking to their GP, and seeking their support, before trying any kind of low calorie diet'.



Like this

loading...
loading...

Latest


06 December 2017
Do young evangelicals care about Israel? Not so much
When asked whether the rebirth of the nation was an injustice to Arabs in the Middle East, 14 percent said they agreed. That is, a growing number of younger Evangelicals are shifting their support away from Israel based on emotivism.

06 December 2017
Delta picks Canadian partner as airline consolidation quietly goes global
Canada's second-biggest airline reports that it has purchased 10 Boeing 787-9 Dreamliners due for delivery by January 2019. "We are delighted to be working with the premier USA carrier, Delta Air Lines , in this joint venture".

06 December 2017
Jaguar Health, Inc. (NASDAQ:JAGX): Financial Health and Analyst Ratings
They expect this year's earnings to rise 3.59% year-over-year to $1.73, followed by 12.72% growth in the next year to $1.95. In terms of Buy, Sell or Hold recommendations, Jaguar Animal Cmn (NASDAQ: JAGX ) has analysts' mean recommendation of 2.

06 December 2017
Empire State Realty Trust, Inc
About 1.56M shares traded or 19.98% up from the average. (NYSE:ESRT) has risen 10.59% since December 6, 2016 and is uptrending. The company has a market cap of $3,262.73, a price-to-earnings ratio of 21.21, a PEG ratio of 5.22 and a beta of 0.98.

06 December 2017
Tillerson Says No Normalization of NATO Ties With Russia
This story has not been edited by Firstpost staff and is generated by auto-feed. Tillerson said he hoped to be at the same reception a year from now.

06 December 2017
Spirit Airlines, Inc. (SAVE) Holdings Lifted by Cambridge Investment Research Advisors Inc
The company has a market cap of $3,010.00, a price-to-earnings ratio of 12.69, a PEG ratio of 1.73 and a beta of 0.75. Citadel Advisors Ltd Llc reported 0.03% stake. (NASDAQ:SAVE). 1.10M were accumulated by Ameriprise Fincl Inc.

06 December 2017
Sells 1516 Shares of Automatic Data Processing (ADP)
Automatic Data Processing, Inc . (NASDAQ: ADP ). 79,520 are held by Azimuth Cap Management Limited Liability Company. The volume of ADP witnessed a shift from 2.29 million shares, based on a 50-day average, to 2.41 million shares.

06 December 2017
The Met Office says Kent is set for snow
A yellow warning for snow has been put in place for the Exmouth, Budleigh, Sidmouth and Honiton areas from 00.05am on Friday (December 8) until 6pm on Saturday (December 9).

06 December 2017
Dallas Sheriff Lupe Valdez, former San Antonian, announces run for governor
Mark White, former San Antonio congressional candidate Tom Wakely, and Dallas businessman Jeffrey Payne. Abbott, now seeking a second term, often polls as the state's most popular elected official.

06 December 2017
Freak airport injury rules Oosthuizen out of Joburg Open
Doug McGuigan is one of the in-form local South Africans contesting this week's Joburg Open at Randpark Golf Club. You know, I just can't do that. "I'm probably going to go do an X-ray today", Oosthuizen said.