Health Care

Bharat Biotech's typhoid vaccine gets World Health Organization prequalification

Typhoid conjugate vaccines (TCVs) are innovative products that have longer-lasting immunity than older vaccines, require fewer doses, and can be given to young children through routine childhood immunization programs, says the WHO. The development of this conjugate vaccine has taken 14 years but it has proved to be effective. Meanwhile, results, published in the Lancet previous year show Tybpar TCV to be 87 percent effective and can also be administered to children over six months old.

SAGE also called for the introduction of TCV to be prioritized for countries with the highest burden of typhoid disease or of antibiotic resistance to Salmonella Typhi, the bacterium that causes the disease. In October 2017, the Strategic Advisory Group of Experts (SAGE) on immunization, which advises World Health Organization, recommended TCV for routine use in children over 6 months of age in typhoid endemic countries. The highest burden of typhoid is due to salmonella typhi.

The total burden of typhoid is 11 to 20 million cases globally.

Typhoid is an acute illness associated with fever. Most typhoid cases in the United States of America are from people who have recently traveled internationally. "For communities where typhoid is common and drug-resistant strains of typhoid are increasing, this presents an opportunity to protect children and adults, save lives and curb risky antimicrobial resistance". Unlocking the potential of vaccines through partnership, Sabin has built a robust ecosystem of funders, innovators, implementers, practitioners, policy makers and public stakeholders to advance its vision of a future free from preventable diseases. For more information, visit and follow us on Twitter, @SabinVaccine.

There are two vaccines to prevent typhoid. Now available typhoid vaccines fail to provide long term protection and protection for children below 2 years of age.

Photo A volunteer, Matthew Speight, drinking a solution containing typhoid during a vaccine trial at Oxford University previous year.

The WHO pre-qualification enables the procurement and supplies of this life saving vaccine to Unicef, the Pan-American Health Organization (PAHO) and GAVI (a vaccine alliance) supported countries. "Recognising the importance of sustained vaccine procurement for low-income and low-middle income countries, we have offered a further price reduction to around $ 1.0 or below/dose, post procurement of 100 million doses for lower and lower-middle income countries", said Dr Krishna Ella, Chairman and Managing Director of Bharat Biotech.

Like this


12 January 2018
Halo 5: Guardians Getting A Free To Play Weekend, Starting Today
To download the game, you'll need about 100-and something GB of free hard drive space and you can find it via the Xbox Store. Xbox owners will be able to play in the game's campaign or in multiplayer modes, including Warzone .

12 January 2018
Waze to be integrated into Ford's infotaiment system
Rather than use the popular app through their phone, Waze users will now be able to use the app via the SYNC 3 touchscreen. The Waze integration will be available in the coming weeks on any 2018 Ford equipped with SYNC 3 version 3.0 or greater.

12 January 2018
US, Canada investigating possible E. coli link to romaine lettuce
On the same date, PHAC said Canada's E. coli outbreak appears to be "ongoing", noting that illnesses continue to be reported. But consumer reports have cautioned consumers to avoid romaine lettuce until the source of the outbreak has been uncovered.

12 January 2018
Bruised heel forces Steyn out of Test and series
Steyn will see an ankle specialist on Sunday, Moosajee said, after which a timeline on his recovery would be clearer. Pace bowling great Dale Steyn's comeback has proved short-lived. "Just feeling very sympathetic for him".

12 January 2018
Verizon A+E Networks Deal Illustrates Growing Digital Reach
A+E Networks pres of distribution David Zagin said the deal doesn't include any content that previously required pay-TV authentication.

12 January 2018
More Than 100 CEOs Pen Letter In Favor Of Protecting Dreamers
The letter claims that allowing the program to expire could cost the U.S. economy $215 billion. That coalition paid for the full-page ads that will run in the Times and Journal Thursday.

12 January 2018
Shares Of Kinder Morgan, Inc. (KMI) bought By MARTIN THOMAS A
The market capitalization (Stock Price Multiply by Total Number of Outstanding Shares) for the company is reported at $43.01B. Jefferies maintained DSW Inc. (NFLX), recently, we noticed that its shares were trading at regions closer to $209.31.

12 January 2018
Renault says new Clio RS 18 has "motorsport breeding"
Renault Sport has unveiled its latest limited-edition model - inspired by the brand's Formula One auto for the upcoming season. It will be launched for European customers in the first half of 2018, with pricing to be announced at a later date.

12 January 2018
Syrian Refugee Given Lifetime Gym Membership After Photo Goes Viral
The effect of the viral photo was such that the owner of the gym made a decision to gift a free lifetime pass to the young boy. As Hussein was pictured standing with his back turned, his face was not visible, making it a hard task to trace him down.

12 January 2018
Occidental Petroleum Corporation (NYSE:OXY) Shares Bought by Patten Group Inc
The consensus recommendation - averaging the work of 11 analysts - of 3.2 for Dean Foods Company (DF ) points to bearish case. Company trades at a P/E ratio of 105.93, and is more expensive than the average stock in the Independent Oil & Gas industry.