Health Care

Herpes virus may have a connection to Alzheimer’s disease

Herpes virus may have a connection to Alzheimer’s disease”

"The hypothesis that viruses play a role in brain disease is not new, but for the first time a study provides strong evidence of this", said the director of the National Institute on Aging Richard Choounts.

In the extensive multicenter study that involved sophisticated "big data" genetic analysis, researchers, didn't expect to find a possible role for human herpesvirus 6A (HHV-6A) and human herpesvirus 7 HHV-7), which are known to cause encephalitis and other chronic conditions.

But that the Herpes viruses might generate a response in the immune system which in turn might increase the collection of a protein called "amyloid" in the brain.

The results, based on tests of brain tissue from almost 1,000 people, found that two strains of herpes virus were far more abundant in the brains of those with early-stage Alzheimer's than in healthy controls.

Scientists have found up to two times higher level of human herpes virus among people with Alzheimer's disease, suggesting the potential role of the viruses in the development of the progressive brain disorder.

"Previous studies of viruses and Alzheimer's have always been very indirect". HSV-1 for example - one that causes cold sores - has been studied in neurodegenerative diseases.

"Our hypothesis is that they put gas on the flame", Joel Dudley, an author of the study and an associate professor of genetics and genomic sciences at the Icahn School of Medicine at Mt. Sinai in New York City, told NPR. Presence of these antibodies indicated the encounters of the person with this virus sometime during their lives.

Ben Readhead, the study's lead author said that the goal of the study was to find ways to understand the disease and treat it better. "The title of the talk that I usually give is, 'I Went Looking for Drug Targets, and All I found Were These Lousy Viruses, ' " he said. "None of them has held up after rigorous cause-effect evaluations".

They found that the virus genes were "talking" to genes in the brain associated with increasing one's risk of Alzheimer's. In 2018, the costs of providing care to individuals with Alzheimer's and other dementias are expected to total more than $277 billion. This was an accidental finding. Identifying links to viruses may help researchers learn more about the complicated biological interactions involved in Alzheimer's, and potentially lead to new treatment strategies. The viruses remain dormant however within the body.

"I don't think we can answer whether herpes viruses are a primary cause of Alzheimer's disease", said Dudley. Gandy also said these findings could open new avenues of research for treatment of the disease but at present risk susceptibility for the disease is still not clearly understood.

Cambridge University academic Dr Alan Howard – who was said to have pioneered the study – said: “This represents one of the most important medical advancements of the century.

Like this



25 June 2018
A massive chocolate cake! Moscow confectioners’ gift for Lionel Messi’s 31st birthday
Argentina now need to win their final game and hope Nigeria beat Iceland in order to have a chance to get out of the group stage. On Thursday they staged an epic second half collapse on their way to losing 3-0 to Croatia.

25 June 2018
Hanley Ramirez allegedly being investigated for drug trafficking
The man's attorney, who asked that he not be named because of concerns it would help identify his client, said "his use of Mr. In hopes of stopping the search, the report says, the driver called Ramirez on FaceTime and handed the phone to the trooper.

25 June 2018
Polls now Closed in Turkish Elections
Women dance under election banners of the pro-Kurdish Peoples' Democratic Party, or HDP, in the mainly-Kurdish city of Diyarbakir. Erdogan, who held five rallies in Istanbul on June 23, called on supporters to be vigilant at the polling stations.

25 June 2018
Match against Argentina like World Cup final, says Rohr
The Nigerian striker has, in fact, attempted just thrice against Iceland - scoring twice, while Messi struck 11 attempts in vain. Ergo, in six World Cup appearances, Musa has two multi-goal games in comparison to Ronaldo (15 matches) and Messi (15 matches).

25 June 2018
Google rolls out offline mode for Chrome on Android
The articles and relevant information will be downloaded automatically for later viewing when no Internet connection is available. Those who are signed into Chrome will also be able to access further articles based on their browsing history, even when offline.

25 June 2018
BRITAIN: 100000 March Against Brexit
Leading Brexit supporters , meanwhile, warned the British government not to delay or water down the divorce from the 28-nation bloc.

25 June 2018
Pakistani celebrities who ordered Melania Trump's jacket online
While we're busy talking about the jacket , we're not focusing on all the disgusting things the administration is doing. And her public statements expressing motherly concerns about the welfare of children often make her husband look bad.

25 June 2018
Roseanne Barr says, 'I made myself a hate magnet'
The interview was not released immediately, as Barr was tearful and emotional while talking about her beloved show. ABC on Thursday announced that this fall it will air a 10-episode Conner family sitcom without Barr in it.

25 June 2018
President Trump Pushes Back On Immigration, Stands With So-Called ‘Angel Families’
They described seeing children sleeping behind bars, on concrete floors and under emergency "mylar" heat-resistant blankets. Goodwin said she has been inundated with requests from the parents, and the list is still growing.

25 June 2018
English bulldog Zsa Zsa wins annual World's Ugliest Dog contest
The 30th World's Ugliest Dog Contest took place this weekend and there were some outstanding entries. Dogs in the competition flaunt their imperfections as they walk down a red carpet with their owners.