Health Care

An Aspirin a Day Won't Make Healthy Adults Live Longer, Study Shows

An Aspirin a Day Won't Make Healthy Adults Live Longer, Study Shows”

Prof John McNeil, from Monash University, said: "It means millions of healthy older people around the world who are taking low dose aspirin without a medical reason, may be doing so unnecessarily, because the study showed no overall benefit to offset the risk of bleeding".

Over a four-year span starting in 2010, the trial enrolled more than 19,000 people in Australia and the United States of America who were 70 and older, or 65 for African-American and Hispanic participants because their risks of dementia or cardiovascular disease are higher.

There is good evidence that taking aspirin can help people with known cardiovascular problems.

Aspirin has been widely used in healthy older adults to protect against cardiovascular disease and cancer. "But not only did it not decrease risk of disability or death, it did not decrease the risk of heart attack and stroke, and there was an increase in the rate of death".

So yes, don't pop aspirin if you are healthy.

Participants took either aspirin or a placebo daily over a four-and-a-half year period.

The trial followed 19,114 seniors - 2,411 from the USA and 16,703 Australians - for an average of 4.7 years.

Older patients experienced no health benefits from taking aspirin, according to the new report, published Sunday in the New England Journal of Medicine.

Undeniably the second study features that the probability of vital hemorrhage was crucially higher with aspirin as compared to placebo.

Doctor Evan Hadley, of the NIA, added: 'Continuing follow-up of the ASPREE participants is crucial, particularly since longer term effects on risks for outcomes such as cancer and dementia may differ from those during the study to date.

McNeil added that a small increase in deaths observed in the aspirin group, primarily from cancer, required further investigation as researchers can not rule out that it may be a chance finding.

One of the more unexpected findings of the study was that people who took aspirin were slightly more likely to have died over the course of the trial from any cause (5.9 percent) than those who took the placebo (5.2 percent). Patients who were black or Hispanic and living in the United States were included in the study as they face a higher risk of heart disease or dementia generally.

But a new Australian-led study has found that's not the case.

The risk is generally calculated using factors such as age, blood pressure, cholesterol levels, smoking history and other conditions such as diabetes. For people older than 70, the task force says it does not have enough information.

At the end of the study, the rate of cardiovascular disease between the two groups of participants was not much different: 9,525 of those taking the aspirin had developed cardiovascular disease compared to 9,589 of those taking the placebo.

They also attributed the higher mortality in this test group to cancer-related deaths.

Clinically significant bleeding - hemorrhagic stroke, bleeding in the brain, gastrointestinal hemorrhages or other hemorrhages that required transfusion or hospitalisation - occurred in 3.8 per cent on aspirin and in 2.7 per cent taking the placebo.



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