5 gene-edited monkeys cloned by China for human disease research

5 gene-edited monkeys cloned by China for human disease research”

Jiankui He, the Chinese scientist whose efforts produced the world's first gene-edited babies, did so through forgery and subterfuge, deliberately skirting the proper channels in the pursuit of personal fame, officials in China told Xinhua News (China's state-run press agency).

Other species were subsequently cloned via the method over the years but primates had until last year proven hard to clone and the team's achievement was hailed as a breakthrough.

Researchers are hopeful that the creation of primates with identical genes and symptoms would help them test new treatments for diseases like brain disorders, cancers etc.

Chinese Academy of Sciences Institute of Neuroscience via CNS shows five cloned macaques at a research institution near Shanghai.

He made headlines around the world when he announced in November past year that he had conducted a clinical trial that involved editing the genes of embryos. It is very disturbing that more such gene edited monkey clones will be produced for the sole goal of further experiments, even if they said this may reduce the number of monkeys used for future experiments. Wang Yue, a health law research at Peking University, spoke to the New York Times describing how China feeds to use this incident as an opportunity to enact stricter regulations as traditionally, "the legal responsibility is unclear and the penalties are very light".

"Disorder of circadian rhythm could lead to many human diseases, including sleep disorders, diabetic mellitus, cancer, and neurodegenerative diseases, our BMAL1-knock out monkeys thus could be used to study the disease pathogenesis as well as therapeutic treatments", said Hung-Chun Chang, senior author and investigator of ION, CAS.

This was then replace with the nucleus from another cell in its body - from a fibroblast, a cell that creates collagen. The cell nucleus was transferred into a seedless egg. This egg then went on to develop into an embryo, and this was then transplanted into a female macaque that later gave birth to the monkey clones.

He embraced the tool, called CRISPR, and previous year rocked an worldwide conference with the claim that he had helped make the world's first gene-edited babies, despite a clear scientific consensus that making genetic changes that could be passed to future generations should not be attempted at this point. They expected to have more monkey clones that carry genetic mutations over the coming years. Meanwhile, the cloning project "paves the way for developing macaque monkey disease models with uniform genetic background".

The researchers plan to continue improving the technique in order to increase the efficiency of cloning.

"This behavior seriously violates ethics and the integrity of scientific research, is in serious violation of relevant national regulations and creates a pernicious influence at home and overseas", a Xinhua News Agency report said.

It is also the same general method used to clone Dolly the sheep more than two decades ago. Furthermore, the study is being supervised by the institute's ethics panel.

Like this



26 January 2019
More plants, less meat, new food guide says
Water should be our "beverage of choice", the guide says, because it keeps us hydrated without adding calories to the diet.

26 January 2019
Gum disease bug could play key role in Alzheimer's, research suggests
The bacteria also boosted production of amyloid beta, a component of brain plaques associated with Alzheimer's, BBC News reported. But she warned that larger clinical trial is needed to see if it will be beneficial to people living with Alzheimer's disease.

25 January 2019
Putin, Abe hold summit to break island impasse
The parliaments of both countries ratified that declaration on December 8, 1956. Russian Federation administers the islands, which are claimed by Japan .

25 January 2019
Felix Tshisekedi Is Sworn In As Congo's President
But he returned to the podium moments after a brief pause, saying he was exhausted by the election and the emotion of the moment. Tshisekedi and Kabila's camps deny that, but Tshisekedi will find it hard to shake Kabila's influence regardless.

25 January 2019
MSP urges north-east woman to go for smear test
It comes as the charity Jo's Cervical Cancer Trust aims to raise awareness during Cervical Cancer Prevention Week. Three million women across England have not had a smear test for at least three and a half years.

25 January 2019
US Commerce Chief to Federal Workers: Get a Loan
Many of those workers are beginning to revolt, either calling in sick or saying they can't afford gasoline. So they are trying to see how long they can hold on financially as the shutdown shows no sign of ending.

25 January 2019
Enes Kanter Upset With Playing Time Against The Rockets
Harden noted afterward that he heard both boos and cheers from the MSG crowd at different points throughout his historic night. Rookie Allonzo Trier scored a season-high 31 points for the Knicks, who lost their seventh straight game.

25 January 2019
Meghan Markle is 'avocado toast whisperer'
The Duchess is a big fan of Soho House , and she and Prince Harry would meet there when they started dating. The visit comes after reports that Meghan's Met Police protection officer has left her post.

25 January 2019
Ray Dalio Says Alexandria Ocasio-Cortez’s Ideas Are Taking Root
Each day presents a fresh opportunity for a conservative to come for Alexandria Ocasio-Cortez online, and without fail, people deliver.

25 January 2019
Smith responds to Derek Carr challenging him to a UFC fight
Derek Carr didn't take kindly to what was said about him on ESPN's First Take this week, and he took it a step further. Yes, yes he did.and quite frankly we don't think the quarterback is being sarcastic.