How cells sense oxygen wins Nobel prize

How cells sense oxygen wins Nobel prize”

Canadian-born scientist James Peebles is one of three researchers who have won this year's NobelPrize in Physics for their contributions to the understanding of the evolution of the universe and Earth's place within it.

Actually, in the case of Kaelin, three people got the unusual wake-up call.

Two Americans and a Briton have won the 2019 Nobel Medicine Prize for discovering a molecular switch that regulates how cells adapt to fluctuating oxygen levels, opening up new approaches to treating heart failure, anaemia and cancer. How cells respond to oxygen The fundamental importance of oxygen, for converting food into energy, has been understood for centuries, but how cells adapt to changes in levels of oxygen has always been unknown.

IT is being challenged with either trying to fix and maintain an already complex system of solution integrations, or exploring driving business impact by unifying its systems under one platform. Cells require oxygen to function and need to adapt to different levels of oxygen in our surroundings, depending on altitude or physical exertion.

The Nobel committee praised the work of the three men saying it "greatly expanded our knowledge of how physiological response makes life possible".

They identified HIF-1a, which appears when oxygen levels are low and disappears when oxygen levels are normal.

The prize is named after Sweden's Alfred Nobel who's most famous for inventing dynamite - a bit unusual when his most famous prize is for peace! "Their discoveries have also paved the way for promising new strategies to fight anemia, cancer and many other diseases". The body plans to award it this year, along with announcing the 2019 laureate. "They were extremely happy, and happy to share the prize with each other", he says. No prize was awarded past year amid sexual harassment and abuse allegations against Jean-Claude Arnault, the husband of an academy member and a recipient of academy funds, according to the Washington Post.

But don't worry, we will have a victor this year. The scandal prompted academy head Sara Danius and others to step down, and Swedish King Carl XVI Gustaf said in a statement the prize announcement would be postponed so the academy could "focus on restoring its reputation".

Alfred Nobel, the Swedish scientist and inventor who made a vast fortune from his invention of dynamite in 1866, ordered the creation of the famous Nobel prizes in his will.

The announcement, October 8, 2019, that a trio of scientists had won the physics Nobel started off with an unlikely reference: the opening lines of "The Big Bang Theory".

The 2019 Nobel Prize in literature will be announced on Thursday, Oct. 10.

"The prize is for this ... rheostat or thermostat of the oxygen levels - a damper that you'd have on your furnace to let in more or less oxygen at any given time so that it's just right, so that the flame burns just right", Johnson said.

How does this help with medicine today?


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