Health Care

Sorrento Therapeutics Says Its Antibody Treatment May Kill Coronavirus

Sorrento Therapeutics Says Its Antibody Treatment May Kill Coronavirus”

Fox News said the company is expected to formally announce its discovery of the STI-1499 antibody, which they say can provide "100% inhibition" of COVID-19, on Friday.

After making the claims, stocks for Sorrento skyrocketed by 244%.

It's one of several antibodies planned to be combined for a drug "cocktail" Sorrento is developing in collaboration with Mt. Sinai School of Medicine in NY. If we have the neutralising antibody in your body, you don't need the social distancing. You can open up a society without fear.

It comes the same day that the Trump administration's social distancing guidelines to slow the spread are expiring, and as many states begin to reopen despite expert warnings that relaxing restrictions may trigger a devastating second wave of infections. Experts have also already warned about the possibility of a second wave of infections once restrictions are lifted.

Sorrento thinks STI-1499 could work both as a stand-alone treatment or as part of an antibody cocktail that targets three different parts of the virus.

The antibody has not yet been tested in people, so how it might behave inside the body and its potential side effects are totally unknown.

STI-1499 is one of about a dozen antibody candidates the company says has demonstrated the ability to prevent SARS-CoV-2 infection of human cells.

More news: Speaking loudly could help spread virus, study finds

Approximately 12 of these antibodies have demonstrated the ability to block the S1 protein's interaction with human angiotensin-converting enzyme 2 (ACE2), the receptor used for viral entrance into human cells.

Among the antibodies showing neutralizing activity, the antibody, STI-1499, stood out for its ability to completely block SARS-CoV-2 infection of healthy cells in the experiments. He added that if the virus can not get inside the cell, it can not replicate or survive.

Ji also told Fox that they have seen in the laboratory how the antibody "wraps around the virus" then takes it away.

The small biotechnology company said it aims to create an antibody cocktail that would act as a "protective shield" against coronavirus.

It's definitely worth cautioning that no treatment or vaccine is likely to be a "magic bullet" in treating SARS-CoV-2 or COVID-19, but this is still a promising development, and one to watch as it undergoes clinical trials and the therapeutic development and regulatory process.

A number of companies and scientific organizations are developing possible treatments for COVID-19, including antibody therapy, vaccines, and pharmaceuticals. However, there is still no proven cure for the coronavirus.



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