Health Care

Steroids cut COVID-19 death rates, but not for everyone

Steroids cut COVID-19 death rates, but not for everyone”

Dexamethasone yielded no increase in secondary infections (21.9% vs 29.1% with standard care), and - albeit with a little more need for insulin for glucose control (31.1% vs 28.3%) - fewer cases of other serious adverse events (3.3% vs 6.1%).

"Although the meta-analysis suggests corticosteroids might not be associated with improved mortality in critically ill patients with COVID-19 and shock, this result is prone to bias by both off-protocol corticosteroid use in the usual care group as well as exclusion of patients already receiving corticosteroids at screening", they added.

The study, led in the United Kingdom by Professor Anthony Gordon from Imperial College London with collaborators from the Intensive Care National Audit & Research Centre, found that patients receiving intensive care who were treated with a regular fixed dose of the steroid hydrocortisone for seven days had a better chance of recovery, compared with the patients who were not treated with the steroid.

'It has also come to notice that patients requiring hospitalisation have to wait for long hours at the triaging area of health facilities before they are shifted to the ICU or put on oxygen and ventilators as per requirement.

Researchers are focusing on whether they could use similar corticosteroid drugs in the part of treatment.

Dexamethasone's benefits for COVID-19 critical illness were replicated in a Brazilian randomized trial, while a World Health Organization-sponsored patient-level meta-analysis of ongoing randomized trials concluded that it's a class effect across corticosteroids. That was great news, but those findings created a conundrum for Angus and other researchers who were running their own studies of steroids in COVID-19 patients. In the groups that were given the various steroids, 30% roughly died. "Which is really impressive to see a result like that".

More news: Why #BoycottMulan is trending again after its Disney+ debut

Simon Stevens, the chief executive of the National Health Service in England, also supported the treatment. He called it the further weapon in the armory in the worldwide fight against COVID-19.

World Health Organization said a "meta-analysis" of seven studies involving over 7,000 participants found steroids like dexamethasone, hydrocortisone and methylprednisolone can reduce the risk of death by up to a third compared to patients who did not receive them.

Studies show that steroids could reduce the risk of death for hospitalized patients on ventilators by about a third.

A new global study published today [02 September] has shown that treating critically ill patients with COVID-19 with the steroid hydrocortisone improves their chances of recovery. We also use these steroids for viral infections. These tests conducted in 88 British hospitals have demonstrated the effectiveness of hydrocortisone, which would save around 1 in 12 patients.

But he added that hydrocortisone is a not a preventive treatment but instead one for severely unwell people in hospital who needed oxygen and were suffering from complications. Researchers from three research groups have now published their findings that they had gathered in the journal JAMA.

The Times' data also shows that the average daily numbers of newly reported coronavirus cases over the past two weeks remained mostly stable in Washington, D.C., and 24 states: Alaska, Arkansas, Colorado, Delaware, Hawaii, Illinois, Indiana, Louisiana, Maine, Maryland, Massachusetts, Michigan, Missouri, New Hampshire, New Jersey, New Mexico, New York, Pennsylvania, Rhode Island, Tennessee, Utah, Vermont, Virginia, and Wisconsin.



Like this

loading...
loading...

Latest


06 September 2020
Satellite Imagery Shows Storm Nana Forming Near Belize
The third tropical disturbance the NHC was tracking is in the northern Atlantic, near Tropical Depression Omar. The storm has maximum sustained winds of 35 mph, and is about 220 miles west-southwest of Belize City.

06 September 2020
Trump to present Holtz with Presidential Medal of Freedom
We've looked at Lou's life and his career, what he's done for charity. "Lou will be getting the Presidential Medal of Freedom . The president did not announce a date for the ceremony but said it 'won't be in the too distant future'.

06 September 2020
Alabama begins payments of $300 for unemployed under federal program
New Hampshire, for example, is supplementing its residents' unemployment benefits to ensure everyone reaches the $100 threshold. Visit the Iowa Department of Human Services website at https://dhs.iowa.gov/disaster-assistance-programs for more information.

05 September 2020
Attorney General Barr: Universal Mail-In Voting 'Playing With Fire'
Treasury approved in July, so that the institution is able to carry out a successful election by mail despite financial troubles. If the mail-in ballot "isn't tabulated", the president said, "they will be able to vote [in person]".

05 September 2020
Miami Dolphins release quarterback Josh Rosen
It also gives Rosen a fresh start and a rare third chance to salvage his National Football League career. According to Adam Schefter, there weren't any teams willing to move pieces for him.

05 September 2020
How PS5's SSD and audio technology will enhance the future of gaming
While these are fairly expected answers, other developers pointed out less obvious benefits to their games. Now, just put on a pair of headphones for a full 3D audio experience".

05 September 2020
Rory McIlroy boosts Tour Championship hopes with brilliant opening 64
Palmer got a bogey on the 469-yard par-4 first, getting on the green in 3 and two putting, moving Palmer to 1 over for the round. It wasn't like I was way off or anything, I just hit quite a few drives just in the rough, which is no good around here".

05 September 2020
Selena Gomez goes makeup-free in LA
She revealed that she didn't really take care of her skin "until the last few years and I realised how important it is". The time has allowed me to really sit with things that may be uncomfortable and to learn so much about what's going on.

05 September 2020
Melbourne Police Clash with Anti-Lockdown Protesters
Some of the demonstrators carried placards with anti-government sentiments and at one stage were singing the national anthem. The only protest we should be engaged in, the only argument, the only fight we should be engaged in is against this virus.

05 September 2020
Russian Federation publishes virus vaccine results, weeks after approval
Instead, a spokeswoman said, the state wants to review the data before agreeing to distribute the vaccine. The vaccine is named Sputnik-V in homage to the world's first satellite, launched by the Soviet Union.