Health Care

Ten more imported COVID-19 cases reported in Mainland China

Ten more imported COVID-19 cases reported in Mainland China”

According to the meta-analysis, the steroid dexamethasone was used in three trials involving a total of nearly 1,300 patients, and seemed to cut the death risk by 36% compared to standard care.

In one trial whose results were published Wednesday in JAMA, the CoDEX trial in Brazil, intensive care patients with moderate to severe acute respiratory distress syndrome (RDS) receiving dexamethasone went ventilator-free for longer than those who got standard care alone-6.6 days versus 4 days, to be specific.

To arrive at the findings of the study, the team pooled data from the seven randomized clinical trials that evaluated the effectiveness of corticosteroids on critically ill patients with COVID-19.

Back in June, a major study from the United Kingdom found that the steroid dexamethasone was actually a big help.

Dr Sabina Sahanic, who worked on the study at the University Clinic in Innsbruck, said: "The bad news is that people show lung impairment from COVID-19 weeks after discharge; the good news is that the impairment tends to ameliorate over time, which suggests the lungs have a mechanism for repairing themselves".

In June, preliminary results of the RECOVERY trial, published in a peer-reviewed paper, were released. That trial found that use of dexamethasone cut the death rate by about one-third for patients on ventilators, and by about one-fifth for those requiring supplemental oxygen. As Prescott and Rice explained, these drugs work to counter the runaway inflammatory response - the so-called "cytokine storm" - that can drive late-stage COVID-19 and overwhelm patients' defenses.

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The COVID-19 cases have been steadily rising in the state and the number is likely to go up further in near future, the official said. Further, the World Health Organization also recommended not to use the treatment in patients with mild to moderate symptoms.

"Moreover, the panel believed that other perspectives (i.e., costs, equity, the feasibility of implementation), and patient values and preferences would not alter decisions".

According to him, the "main utility" of this product will replace another steroid already recognized to be effective, dexamethasone, in order to overcome the "drug stock problem", main difficulty during a global pandemic that affects "millions of patients".

Corticosteroids are a class of steroid hormones that lowers inflammation in the body as well as reduce the immune system's activity.

By the end of Saturday, a total of 2,573 imported cases had been reported on the mainland.



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