Health Care

Halting COVID-19 trial shows good oversight, says Wits' Prof Madhi

Halting COVID-19 trial shows good oversight, says Wits' Prof Madhi”

A volunteer receives an injection at the Chris Hani Baragwanath hospital in Soweto, Johannesburg - the first participation in a Covid-19 vaccine trial developed at the University of Oxford.

The European Commission signed a pre-purchase agreement with AstraZeneca for a coronavirus vaccine on August 27.

Russian Federation announced the development of the "Sputnik-V" vaccine, the world's first registered coronavirus vaccine as proof of its scientific prowess. "We may probably allow Phase III work for the vaccine in Russian Federation next week", he said, adding 13 different Turkish vaccine efforts were underway in Turkey, but only at pre-Phase I levels so far.

The woman's symptoms were consistent with transverse myelitis, a serious spinal inflammatory disorder that can cause bladder problems, muscle weakness, pain and at worst, paralysis.

She said scientists should not be discouraged by the development.

And even unrelated health events in vaccine participants - such as a broken bone - are regarded as adverse reactions that can lead to a pause.

The Independent Data and Safety Monitoring Committee has recommended further vaccination of candidates be temporarily halted while it investigates the United Kingdom case which saw a trial participant fall ill.

Linking such an autoimmune response to a single factor like a vaccine is problematic, he said, given the number of immunological, hormonal or environmental factors at play.

"We can't bank on a vaccine".

More news: New Zealand lining up options, including the Boks if Rugby Championship canned

"We will be guided by this committee as to when the trials could restart, so that we can continue our work at the earliest opportunity", Soriot said in a statement.

"And I think there's a reasonable chance that. we can think about the possibility of vaccination next year sometime at larger levels". "We have to manage it".

"This certainly happens in any large-scale trial where you have tens of thousands of people invested in taking part".

He added that the company aims to have the manufacturing capacity to distribute the vaccine worldwide by early next year.

"But ... there is no guarantee that this, or any other, vaccine will be successful, which is why we are continuing our discussions with many parties around the world while backing our own researchers at the same time to find a vaccine".

AstraZeneca says it should know before the end of the year whether its experimental vaccine will protect people from Covid-19.

In India, the Serum Institute of India (SII) is the partner of the University of Oxford's Jenner Institute to conduct vaccine trials.

The Russian Sputnik-V vaccine is administered in two doses, with each based on a different vector that normally causes the common cold: human adenoviruses Ad5 and Ad26.

After vaccination, this protein is produced inside the human body, which primes the immune system to attack the coronavirus if the person is later infected.



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