Health Care

Early Trials Of Chinese Company's Vaccine Show It Triggers An Immune Response

Early Trials Of Chinese Company's Vaccine Show It Triggers An Immune Response”

"That is a concern", said Thomas Campbell, associate dean for clinical research at the University of Colorado, of the low antibody levels in Sinovac's Phase 2 trial.

This, the biotech said, is based on its experience with other vaccines and data from preclinical studies with macaques.

The journal said, the vaccine appeared to be safe and well tolerated at all tested doses.

"Our findings show that CoronaVac is capable of inducing a quick antibody response within four weeks of immunisation by giving two doses of the vaccine at a 14-day interval", said study author Fengcai Zhu from the Jiangsu Provincial Center for Disease Control and Prevention in China.

However, Johnson & Johnson's vaccine had snafus of its own, including a pause in the phase 3 trial that launched in late September due to a serious medical event in one of its participants. Phase III results must be published to provide a more conclusive picture, said Naor Bar-Zeev, a professor from Johns Hopkins University who was not involved in the study, said.

More news: Aramco plans debt market comeback with multi-tranche bond deal

As companies around the world race to develop coronavirus vaccines, hundreds of thousands of people in China were inoculated with a vaccine before its efficacy was proven in trials. Although the federal government then pumped another $1 billion into the creation of the vaccine, leading researcher Dr Mark Denison stressed it was Ms Parton's investment that funded the "critical" early stages of his team's work.

The vaccine can be stored at normal fridge temperatures of two to eight degrees Celsius (36°-46°F) and may remain stable for up to three years. "(It) would offer some advantages for distribution to regions where access to refrigeration is challenging", he said.

Yep, the "Jolene" hitmaker, 74, is being credited for "curing coronavirus" by fans after it emerged that she has donated $1million (£800,000) to the researchers behind the Moderna vaccine - which is so far showing the most promising results globally.

Pfizer's vaccine must be stored and transported at minus 70 deg C, though it can be kept in a normal fridge for up to five days, or up to 15 days in a thermal shipping box.

"It's one thing to be effective two months after your last vaccination and another thing to be effective a year" later, said Dr Jesse Goodman of Georgetown University, a former director of the FDA's vaccine division. While CoronaVac was produced with tried-and-true methods, the mRNA technology is new, and there hasn't been an mRNA vaccine approved by the Food and Drug Administration before.



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