Health Care

AstraZeneca vaccine shows strong immune response in elderly, appears safe in study

AstraZeneca vaccine shows strong immune response in elderly, appears safe in study”

"As a result, it is crucial that COVID-19 vaccines are tested in this group who are also a priority group for immunization", he said in a news release from the journal The Lancet.

Besides the recipients of the Sinopharm jabs, authorities in Zhejiang said they had made a COVID-19 vaccine developed by the privately owned pharmaceutical company Sinovac Biotec available to high-risk groups in the east China province under the emergency use scheme. One group of the volunteers was given two treatments of the vaccine, called ChAdOx1.

The AstraZeneca/ Oxford vaccine is now in phase 3 trials, which are set to determine its efficacy.

As Axios reported, the next step for the vaccine candidate is to enter Phase III trials, in which the initial clinical group is expanded even further to a larger and more diverse group of participants.

The study's findings, which looked only at data from the phase 2 trial, are important because older adults often have a lessened immune response and are more susceptible to infections, explained the study's lead author, Andrew Pollard. The ongoing study is a single-blind, multicenter, randomized, controlled phase II/III safety and efficacy study.

More news: World Health Organization recommends against use of remdesivir for Covid-19 hospitalised patients

Study recruitment occurred during a national lockdown in the United Kingdom when vulnerable individuals were advised to self-isolate. Those individuals who received two doses had their immune responses assessed on the day of vaccination, and day 1, day 2, and 4 weeks post-vaccination. The incidence of adverse reactions in the 3 micrograms and 6 microgram groups were similar.

LONDON, Nov 20 ― A leading Covid-19 vaccine candidate has shown to safely produce a robust immune response in healthy older adults, its British makers said yesterday as it released its phase 2 trial results.

"One of the most exciting things from our study was that the vaccine stimulated really good antibody production". T-cell response occurred within 14 days of the first dose of vaccination, and antibody response occurred within 28 days of the booster dose of vaccination. And, crucially, the researchers wanted to know if it might work in older people who are most at risk of severe Covid.

"What this could mean is that in the future when we're looking to boost people's responses, we might need to do it more often in older people than we do with younger people, but we're not thinking that we're going to need to boost people a few times a year as we do with the flu vaccine". While CoronaVac was produced with tried-and-true methods, the mRNA technology is new, and there hasn't been an mRNA vaccine approved by the Food and Drug Administration before.



Like this

loading...
loading...

Latest


20 November 2020
Deadly COVID-19 Case Numbers Soar In LA: Officials Sound 'Alarm'
Two senior administration officials told CBS News that doctors believe that in just a week, the USA may see 1,500 deaths a day. The county previously issued guidance limiting gatherings to three households, but there was no numerical limit on attendees.

20 November 2020
Disney+ Debuts Trailer For New Christmas Movie "Godmothered"
Godmothered is set at Christmastime, so Disney+ is clearly trying to capitalize on the need for an uplifting holiday movie . Jillian Bell is pitch flawless casting for a role like this, bringing the right amount of whimsy and comedy.

20 November 2020
Pa. sharpens mask mandate, orders virus testing
The order does not apply to people who commute to and from another state for work or medical treatment. Thomas Farley, said at a news conference Monday as the city battles a resurgence of the coronavirus.

20 November 2020
Powered Macs Can Already Run Windows Apps Using CrossOver
So much so that you can use it to play action-packed online games on a MacBook Air that doesn't even have a fan. Coming to the M1-powered MacBook Pro, the cooling system is very similar to the Intel-based predecessor.

20 November 2020
Meghan Markle Reveals Contribution to Unauthorized Biography 'Finding Freedom'
Meghan Markle has revealed the extent of her role in the creation of unauthorized biography " Finding Freedom ". It says she wanted to correct the false impression conveyed by Thomas Markle "that she had abandoned him".

20 November 2020
Biden chides Trump for lack of co-operation on vaccine
Trump's campaign has cited "irregularities" in the counties, although no evidence of illegal activity has been presented. In Arizona , a judge was set to decide on a Republican push to block the certification of election results for the state.

20 November 2020
Luke Kennard trade improves Clippers bench during an active draft night
Detroit selected the Franklin High School graduate and Duke alum with the No. 12 pick in 2017 . He will replace Shamet, a 40% three-point shooter during his two seasons as a pro.

20 November 2020
Cyberpunk 2077 - Night City Wire Episode 5, new gameplay trailer and screenshots
In the lead-up to launch, the game has hosted Night City Wire streams to share more information about the game. This is a start-to-finish examination of what you'll be doing, and why, in Cyberpunk 2077's open world.

20 November 2020
UK Mom gives birth to twins while in COVID coma
Since being discharged from the hospital after almost three months in the ICU, Uke said the twins are "getting better" each day. "They were so tiny they didn't look like my older kids, I couldn't touch them, I felt so emotional", she told the outlet.

20 November 2020
Hungary says it blocked European Union budget over migration 'blackmail'
Those who protect their borders can not qualify as countries where rule of law prevails", he said in a statement released to the state news agency MTI.